2019-10-09RELPDBjPDBjPDBj2019-08-232019-09-182019-09-182019-10-09National Basic Research Program of China(973 Program)2017YFA0503503ChinaNational Natural Science Foundation of China31872714ChinaNational Natural Science Foundation of China31670754ChinaNational Natural Science Foundation of China31861143028ChinaTRiC at 0.05 mM ADP-AlFx, Conformation 3, 0.05-C3Jin MCong YJin MHan WLiu CZang YLi JWang FWang YCong YAn ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.Proc.Natl.Acad.Sci.USAUS1161951319522201931492816doi:10.1073/pnas.19039761161091-64900040PNASA6EMD-0756other EM volumeTRiC structure at different nucleotide and concentrationEMD-0765associated EM volumeTRiC complexTRiC complex0123456789TRiC complex at 0.05 mM ADP-AlFxSaccharomyces cerevisiae0.96singleParticleparticle17.5ETHANEFEI TITAN KRIOSFLOOD BEAMBRIGHT FIELDFIELD EMISSION GUN300GATAN K2 SUMMIT (4k x 4k)38.017.18FSC 0.143 CUT-OFF24450MAXIMUM LIKELIHOODMAXIMUM LIKELIHOOD