2021-05-19RELPDBjPDBjPDBj2021-04-132021-05-052021-05-052021-05-19Human Mediator (deletion of MED1-IDR) Tail moduleYin XLi JWu ZLiu WXu YChen XYin XLi JWu ZQi YWang XLiu WXu YStructures of the human Mediator and Mediator-bound preinitiation complex.ScienceUS202133958484doi:10.1126/science.abg06351095-92030038SCIEASEMD-31191other EM volumeEMD-31194associated EM volumeStructure of the human Mediator complexStructure of the human Mediator complex0123456789101112131415161718192021222324252627Homo sapiensHomo sapiensExpi293singleParticleparticle8.0Quantifoil R1.2/1.3GOLDCARBONHOLEYETHANE100FEI VITROBOT MARK IVFEI TITAN KRIOSFLOOD BEAMBRIGHT FIELDFIELD EMISSION GUN30070.02.7FEI TITAN KRIOS AUTOGRID HOLDERNITROGEN20GATAN K2 SUMMIT (4k x 4k)SUPER-RESOLUTION50.013.2FSC 0.143 CUT-OFF98988OTHERMAXIMUM LIKELIHOODAB INITIO MODELREAL