Information about the masks which have been taken from the tomogram map emd_1273.map

emd_1273_msk_1.map:mask1_synapse:
Synaptic cleft, i.e. space between the CTL and the target cell as
defined by the opposing membranes. Areas of close membrane-membrane
contact (adhesion/signaling domains) and pocket-like areas with larger
membrane-membrane distances (secretion domain) are clearly
distinguishable.

emd_1273_msk_2.map:mask2_MTs:
Microtubule (MT) network within the CTL. The MTs radiate out from the
polarized centrosomal area, running both away from the plasma membrane
into the cell and along the cell membrane to the periphery of the
synapse. Both lytic granules (see mask granules_mask4) and the Golgi
apparatus (see mask golgi_mask5) are linked to and transported along the
MTs to the synaptic cleft.

emd_1273_msk_3.map:mask3_centriole:
One of the two CTL centrioles, sitting close to the synaptic cleft. The
two centrioles form part of the centrosome that is polarized to the
synaptic cleft. Microtubules run from here into the cell and along the
cell membrane to the periphery of the synapse (see mask MTs_mask).

emd_1273_msk_4.map:mask4_granules:
The lytic granules are the "cytotoxic organelles" of the CTL. They are
transported along the MTs in a minus-end fashion towards the polarized
centrosome. After docking to the cell membrane they probably fuse with
the membrane at the secretory domain and excrete the cytotoxic proteins
into the synaptic cleft.

emd_1273_msk_5.map:mask5_golgi:
A CTL Golgi apparatus, sitting close to the synaptic cleft. The Golgi
apparatus is polarized to the cell-cell contact together with the
centrosome.